Influence of resection width on the rate of local recurrence in combined treatment of soft tissues sarcomas

V. V. Teplyakov; Тепляков В. В.; V. U. Karpenko; Карпенко В. Ю.; G. A. Frank; Франк Г. А.; A. A. Bulanov; Буланова А. А.; A. V. Bondarev; Бондарев А. В.; I. V. Droshneva; Дрошева И. В.; V. A. Derzhavin; Державин В. А.; A. V. Bukharov; Бухаров А. В.

Influence of resection width on the rate of local recurrence in combined treatment of soft tissues sarcomas

Authors: Teplyakov V.V.¹, Karpenko V.U.¹, Frank G.A.¹, Bulanov A.A.¹, Bondarev A.V.¹, Droshneva I.V.¹, Derzhavin V.A.¹, Bukharov A.V.¹
Affiliations:
1. P.A. Hertcen Moscow Cancer Research Center
Issue: Vol 1, No 1 (2009)
Pages: 28-33
Section: SOFT TISSUE SARCOMAS
Published: 11.01.2009
URL: https://sarbon.abvpress.ru/jour/article/view/132
ID: 132

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Purpose. To evaluate the influence of resection width on the rate of local recurrence in patients with soft tissues sarcomas. Materials and methods. 30 patients (16 male, 14 female) were observed. The mean age was 44 years old. There were 14 (47%) patients with initial tumors, and 16 (53%) with local recurrence after the treatment. All patients receive neoadjuvant chemotherapy. Neoadjuvant radiation therapy was performed in 6 (19%) patients. All patients had surgical treatment done in time. The mean tumor volume was 1540 cm³. The adjuvant treatment was performed in 18 (69%) patients (chemotherapy inll, radiology in 4, both methods in 1 and surgical treatment of lungs metastasis in 2 patients). Results. The mean size of resection margins was 20mm. The mean follow up was 26 months. The local control rate was 87%. Disease free interval was 19 (63%), overall survival - 22 (73%). Resume. Combined method with radiology in treatment of patients with soft tissues sarcomas has specific advantages in a contrast with surgical treatment alone, and provides better disease free interval and overall survival.

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chemotherapy, long term results, soft tissues sarcomas

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Influence of resection width on the rate of local recurrence in combined treatment of soft tissues sarcomas

Full Text

Abstract

Keywords

About the authors

References

Supplementary files