Cutaneous malignant melanoma in children and adolescents in russia: population-based epidemiological study

The aim of this study was to investigate the cutaneous malignant melanoma (CMM) in individuals aged under 20 years in Russia. We consider both temporal and geographical variations. The Annual reports of Ministry of health and Federal State Statistics Service were used to extract information on cases (1990-2009) and deaths (1999-2009) including gender, age and geographic information. Population data were also obtained and analyses included descriptive summaries, rates, and trend detection tests. During 20 fiscal years, 1860 children and adolescent were diagnosed with CMM. Significant temporal variation of incidence was observed: increase in 1990s (AAPC=9,5%; [95%HR 7,1% ь -12%]) following by decline in 2000s (AAPC= -13,4% [95%HR -17,9% - -12%]). There were a doubling of average Russia incidence rates in some areas. Mortality from childhood CMM was sufficiently high in 1999-2009 (0,25 per 1000,000). Conclusion: although a relatively rare number of children and adolescent in Russia were diagnosed with CMM during the study period, significant temporal and geographical variations were found. Further study is required to explain higher rate areas.

cutaneous malignant melanoma, children and adolesents, epidemiology