Intraoperative radiation therapy in combined treatment of soft tissue sarcomas

A. A. Kurilchik; Курильчик А. А.; A. L. Zubarev; Зубарев А. Л.; A. L. Starodubtsev; Стародубцев А. Л.; V. E. Ivanov; Иванов В. Е.; Yu. V. Gumenetskaya; Гуменецкая Ю. В.; A. A. Zheravin; Жеравин А. А.; G. S. Zhamgaryan; Жамгарян Г. С.

Intraoperative radiation therapy in combined treatment of soft tissue sarcomas

Authors: Kurilchik A.A.¹, Zubarev A.L.¹, Starodubtsev A.L.¹, Ivanov V.E.¹, Gumenetskaya Y.V.¹, Zheravin A.A.¹, Zhamgaryan G.S.¹
Affiliations:
1. A.F. Tsyb Medical Radiological Research Center – branch of the Federal State Budget Institution «National Medical Radiological Research Center» of the Health Ministry of the Russian Federation
Issue: Vol 9, No 2 (2017)
Pages: 39-45
Section: SOFT TISSUE SARCOMAS
Published: 16.04.2017
URL: https://sarbon.abvpress.ru/jour/article/view/329
ID: 329

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Abstract

Soft tissue sarcomas (STS) are an uncommon group of malignancies, notorious for a high propensity for recurrence and early, mainly hematogenous, metastasizing. Nowadays, combined modality therapy involving radical organ preservation surgery in conjunction with various chemoradiotherapy regimens is the treatment method of choice for STS. In order to improve the efficacy of organ preservation treatment, it is necessary to intensify local treatment of risk areas. Intraoperative radiation therapy (IORT) is one of the methods for intensifying local treatment. In our study, advantages and prospects of development of this approach to combination and concurrent treatment of STS are considered.