Low-grade central osteosarcoma. Review

D. V. Rogozhin; Рогожин Д. В.; D. M. Konovalov; Коновалов Д. М.; A. G. Talalaev; Талалаев А. Г.; V. Yu. Roschin; Рощин В. Ю.; N. A. Bolshakov; Большаков Н. А.; M. V. Tikhonova; Тихонова М. В.; A. N. Remizov; Ремизов А. Н.

Low-grade central osteosarcoma. Review

Authors: Rogozhin D.V.¹^,2, Konovalov D.M.¹^,2, Talalaev A.G.¹^,2, Roschin V.Y.¹^,2, Bolshakov N.A.¹^,2, Tikhonova M.V.¹^,2, Remizov A.N.¹^,2
Affiliations:
1. Russian Children’s Clinical Hospital
2. Research Center of Pediatric Hematology, Oncology and Immunology
Issue: Vol 8, No 3 (2016)
Pages: 16-21
Section: BONE SARCOMAS
Published: 22.10.2016
URL: https://sarbon.abvpress.ru/jour/article/view/360
ID: 360

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Abstract

Low-grade central osteosarcoma is a rare subtype of intramedullary osteosarcoma (approximately 1% of all osteosarcomas) that characterized histologically by a spindle cell proliferation associated with trabecular bone formation, and is usually located in the long bones with a predilection for the distal femur and proximal tibia. It has the potential to recur, dedifferentiate, and metastasize subsequent to surgical treatment. Sometimes it is difficult to make a diagnosis and differentiate it with fibrous dysplasia and desmoplastic fibroma. In such cases, careful radiological interpretation is helpful. This tumor usually carries a good prognosis.