S-100B Protein and its diagnostic value in melanoma

Abstract

We evaluated serum S-100B protein in 45 patients with melanoma and in 40 healthy donors as a control group. Results revealed elevation of S-100В in cases with primary tumors and cases with recurrent disease. Test sensitivity was 63%, specificity – 72,5%, accuracy – 67,4%. S-100B is primary diagnostic marker that may predict disease progression but further studies are needed.