Isoleted limb regional perfusion in the combined treatment of patients with soft tissue sarcomas of the limbs

Soft tissue sarcoma (STS) – a heterogeneous group of tumors, which includes about 50 subtypes. generally STS are located on the extremities. The aim of the study is to analyze the possibility of using of isolated regional perfusion of extremities in the treatment of soft tissue sarcomas. According to major studies, the percentage of responses after the ILP is 70%, while a complete response develops in 20% of cases. Despite numerous studies and their optimistic results, the problem of the treatment of locally common extremity soft tissue sarcomas has not been fully resolved. To increase the efficiency of the ILP with melphalan and its wider use in the practice of specialized clinics the basic parameters of its implementation must be clearlyworked out, a patient selection criteria for integrated and combined treatment with the use of the ILP must be clearly formed.