Juvenile ossifying fibroma in children. Problems in differential diagnosis

Juvenile ossifying fibroma (JOF) is a group of heterogeneous benign fibro-osseous tumors of the craniofacial skeleton in young people. According to the WHO, JOF may present as one of two histologic variants: juvenile psammomatoid ossifying fibroma (JPOF) and juvenile trabecular ossifying fibroma (JTOF). Radiographycally, JOF presents as a well defined, unilocular or multilocular, expansive radiolucency with cortical thinning. The definitive diagnosis of JOF should be based on clinical and radiographic findings, in conjunction with the histopathologic characteristics of the lesion.