Clinical case of treatment of secondary chondrosarcoma developed due to Ollier disease

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Abstract

Ollier disease is a rare non-hereditary disorder of the bone tissue characterized by development of multiple benign bone tumors – enchondromas. One of the dangerous complications of this pathology is tumor transition into chondrosarcoma. Currently, there are no drug therapies for Ollier disease. Surgical treatment is performed in case of complications (chondrosarcoma, pathological fracture).

The article presents a clinical case of chondrosarcoma treatment  in a 42-year-old male with Ollier disease diagnosed when the patient was 8 years old. Since 2021, the patient noted intensive tumor growth on the right foot and left calf. In August of 2022, the patient sought medical help at the Republican Clinical Oncological Dispensary of the Bashkortostan Ministry of Health. Examination showed synchronous malignant transformation of enchondromas of the right foot and left calf confirmed by histological exam. Due to tumor advancement, surgical treatment  was performed. Other enchondroma lesions are being watched.

About the authors

M. M. Zamilov

Republican Clinical Oncological Dispensary, Ministry of Health of Republic of Bashkortostan

Author for correspondence.
Email: zamartin@mail.ru
ORCID iD: 0000-0003-0918-3993

Marat M. Zamilov.

73/1 Prospekt Oktyabrya, Ufa 450054, Republic of Bashkortostan

Russian Federation

K. V. Menshikov

Republican Clinical Oncological Dispensary, Ministry of Health of Republic of Bashkortostan; Bashkir State Medical University, Ministry of Health of Russia

ORCID iD: 0000-0003-3734-2779

73/1 Prospekt Oktyabrya, Ufa 450054, Republic of Bashkortostan; 3 Lenin St., Ufa 450008, Republic of Bashkortostan

Russian Federation

Sh. I. Musin

Republican Clinical Oncological Dispensary, Ministry of Health of Republic of Bashkortostan; Bashkir State Medical University, Ministry of Health of Russia

ORCID iD: 0000-0003-1185-977X

73/1 Prospekt Oktyabrya, Ufa 450054, Republic of Bashkortostan; 3 Lenin St., Ufa 450008, Republic of Bashkortostan

Russian Federation

A. V. Sultanbayev

Republican Clinical Oncological Dispensary, Ministry of Health of Republic of Bashkortostan

ORCID iD: 0000-0003-0996-5995

73/1 Prospekt Oktyabrya, Ufa 450054, Republic of Bashkortostan

Russian Federation

I. A. Sharifgaliev

Republican Clinical Oncological Dispensary, Ministry of Health of Republic of Bashkortostan; Bashkir State Medical University, Ministry of Health of Russia

ORCID iD: 0000-0002-8334-4639

73/1 Prospekt Oktyabrya, Ufa 450054, Republic of Bashkortostan; 3 Lenin St., Ufa 450008, Republic of Bashkortostan

Russian Federation

S. V. Osokin

Republican Clinical Oncological Dispensary, Ministry of Health of Republic of Bashkortostan

ORCID iD: 0000-0003-4639-962X

73/1 Prospekt Oktyabrya, Ufa 450054, Republic of Bashkortostan

Russian Federation

V. S. Chalov

Republican Clinical Oncological Dispensary, Ministry of Health of Republic of Bashkortostan

ORCID iD: 0000-0001-8779-4074

73/1 Prospekt Oktyabrya, Ufa 450054, Republic of Bashkortostan

Russian Federation

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Copyright (c) 2023 Zamilov M.M., Menshikov K.V., Musin S.I., Sultanbayev A.V., Sharifgaliev I.A., Osokin S.V., Chalov V.S.

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