Case report: role of multidisciplinary approach in a case of spine osteosarcoma with oligometastatic heart disease

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Introduction. Primary spinal osteosarcoma and rare metastatic heart lesion are considered significant factors for poor prognosis. The available work indicates that combined treatment, including the radical surgery of heart solitary metastatic lesion, probably provides the best outcome.

Case report. Man, 27-year-old, with Th8 spinal osteosarcoma and solitary left atrial metastasis. From October 2019 to February 2020 5 cycles of chemotherapy (high doses of platinum and doxorubicin) were carried out with positive effect. Next steps were surgery: March 2020 – spondylectomy of the Th8 vertebra with combined stabilization; September 2020 – subtotal resection with plasty of the right atrium, tricuspid valve and prosthesis of the right coronary artery. Between the first and second surgery, 4 more same chemotherapy cycles were carried out. Currently, 24 months after completion of treatment, there are no signs of the disease.

Conclusion. The article presents a unique case of treatment of primary osteosarcoma and metastatic lesion of rare location. Multidisciplinary approach and combination treatment in specialized centers increase the probability of favorable outcome in such cases.

About the authors

A. A. Tararykova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Author for correspondence.
Email: anastasiatararykova@gmail.com
ORCID iD: 0000-0002-5548-3295

Anastasia Alekseevna Tararykova

24 Kashirskoe Shosse, Moscow 115522

Russian Federation

A. K. Valiev

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

ORCID iD: 0000-0002-2038-3729

24 Kashirskoe Shosse, Moscow 115522

Russian Federation

P. V. Kononets

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

ORCID iD: 0000-0003-4744-6141

24 Kashirskoe Shosse, Moscow 115522

Russian Federation

E. R. Charchyan

B.V. Petrovsky Russian Surgery Research Center

ORCID iD: 0000-0003-3164-2877

2 Abrikosovsky Lane, Moscow 119991

Russian Federation

R. M. Kabardaev

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

ORCID iD: 0000-0001-9482-2504

24 Kashirskoe Shosse, Moscow 115522

Russian Federation

A. V. Fedorova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

ORCID iD: 0000-0002-4516-3255

24 Kashirskoe Shosse, Moscow 115522

Russian Federation

G. S. Batyrova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

ORCID iD: 0000-0002-6932-0059

24 Kashirskoe Shosse, Moscow 115522

Russian Federation

A. R. Shin

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

ORCID iD: 0000-0002-3595-3472

24 Kashirskoe Shosse, Moscow 115522

Russian Federation

N. A. Kozlov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

ORCID iD: 0000-0003-3852-3969

24 Kashirskoe Shosse, Moscow 115522

Russian Federation

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Copyright (c) 2023 Tararykova A.A., Valiev A.K., Kononets P.V., Charchyan E.R., Kabardaev R.M., Fedorova A.V., Batyrova G.S., Shin A.R., Kozlov N.A.

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