<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Bone and soft tissue sarcomas, tumors of the skin</journal-id><journal-title-group><journal-title xml:lang="en">Bone and soft tissue sarcomas, tumors of the skin</journal-title><trans-title-group xml:lang="ru"><trans-title>Саркомы костей, мягких тканей и опухоли кожи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2219-4614</issn><issn publication-format="electronic">2782-3687</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">238</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">MISTAKES AND COMPLICATIONS IN THE TREATMENT OF SOFT TISSUE SARCOMAS</article-title><trans-title-group xml:lang="ru"><trans-title>Ошибки и осложнения при лечении сарком мягких
тканей</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Буров</surname><given-names>Д. А.</given-names></name><address><country country="RU">Russian Federation</country></address></contrib><contrib contrib-type="author"><name><surname>Бохян</surname><given-names>Б. Ю.</given-names></name><address><country country="RU">Russian Federation</country></address><email>bbokhyan@eesg.ru</email></contrib><contrib contrib-type="author"><name><surname>Хусейнов</surname><given-names>З. Х.</given-names></name><address><country country="RU">Russian Federation</country></address></contrib><contrib contrib-type="author"><name><surname>Феденко</surname><given-names>А. А.</given-names></name><address><country country="RU">Russian Federation</country></address></contrib><contrib contrib-type="author"><name><surname>Мартынков</surname><given-names>Д. В.</given-names></name><address><country country="RU">Russian Federation</country></address></contrib><contrib contrib-type="author"><name><surname>Хайленко</surname><given-names>В. А.</given-names></name><address><country country="RU">Russian Federation</country></address></contrib><contrib contrib-type="author"><name><surname>Burov</surname><given-names>D. A.</given-names></name><address><country country="RU">Russian Federation</country></address></contrib><contrib contrib-type="author"><name><surname>Bokhyan</surname><given-names>B. U.</given-names></name><address><country country="RU">Russian Federation</country></address></contrib><contrib contrib-type="author"><name><surname>Huseinov</surname><given-names>Z. H.</given-names></name><address><country country="RU">Russian Federation</country></address></contrib><contrib contrib-type="author"><name><surname>Fedenko</surname><given-names>A. A.</given-names></name><address><country country="RU">Russian Federation</country></address></contrib><contrib contrib-type="author"><name><surname>Martynkov</surname><given-names>D. V.</given-names></name><address><country country="RU">Russian Federation</country></address></contrib><contrib contrib-type="author"><name><surname>Khaylenko</surname><given-names>V. A.</given-names></name><address><country country="RU">Russian Federation</country></address></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="ru">Российский онкологический научный центр им. Н.Н. Блохина РАМН</institution></aff><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="ru">Онкологический научный центр Республики Таджикистан</institution></aff><aff><institution xml:lang="en">Tajikistan Cancer Research Center</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2011-07-11" publication-format="electronic"><day>11</day><month>07</month><year>2011</year></pub-date><volume>3</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>29</fpage><lpage>36</lpage><history><date date-type="received" iso-8601-date="2022-01-11"><day>11</day><month>01</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, ., ., ., ., ., ., Burov D.A., Bokhyan B.U., Huseinov Z.H., Fedenko A.A., Martynkov D.V., Khaylenko V.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, Буров Д.А., Бохян Б.Ю., Хусейнов З.Х., Феденко А.А., Мартынков Д.В., Хайленко В.А., Burov D., Bokhyan B., Huseinov Z., Fedenko A., Martynkov D., Khaylenko V.</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">., ., ., ., ., ., Burov D.A., Bokhyan B.U., Huseinov Z.H., Fedenko A.A., Martynkov D.V., Khaylenko V.A.</copyright-holder><copyright-holder xml:lang="ru">Буров Д.А., Бохян Б.Ю., Хусейнов З.Х., Феденко А.А., Мартынков Д.В., Хайленко В.А., Burov D., Bokhyan B., Huseinov Z., Fedenko A., Martynkov D., Khaylenko V.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://sarbon.abvpress.ru/jour/article/view/238">https://sarbon.abvpress.ru/jour/article/view/238</self-uri><abstract xml:lang="en"><p>The outcome of soft tissue sarcoma (STS) surgery depends on many different factors, including the quality of surgical treatment. Adequate surgical treatment provides stable control of the disease. Local recurrence is a key factor in evaluating the quality of performed surgical treatment. The article reviews main predictor factors, based on the results of numerous studies, which allow to perform reliable evaluation of tumor expansion and criteria of surgical treatment quality in STS. The article gives comprehensive description of signs and symptoms of main postoperative complications. Attention is paid to typical mistakes, leading to considerable increase of local recurrence and associated survival decrease; preventive measures are emphasized</p></abstract><trans-abstract xml:lang="ru"><p>Результаты лечения СМТ зависят многих факторов, в том числе и от качества хирургического вмешательства. Грамотное хирургическое лечение позволяет добиться стойкого контроля над заболеванием. Ключевым фактором в оценке качества проведенного хирургического вмешательства является местное рецидивирование опухоли. В статье приводятся прогностические факторы, основанные на результатах многочисленных исследований, позволяющие с высокой степенью достоверности определить распространенность процесса, а также критерии качества хирургического вмешательства при лечении СМТ, подробно описаны варианты и признаки возникновения послеоперационных осложнений. Также в статье обращено внимание на типичные ошибки, приводящие к резкому повышению частоты местных рецидивов и снижению выживаемости, методы их профилактики</p></trans-abstract><kwd-group xml:lang="en"><kwd>soft tissue sarcoma</kwd><kwd>surgical treatment</kwd><kwd>recurrence</kwd><kwd>postoperative complications</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>саркома мягких тканей</kwd><kwd>хирургическое лечение</kwd><kwd>рецидивирование</kwd><kwd>послеоперационные осложнения</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Кочнев В.А. Клиника, дифференциальная диагностика и стадирование сарком мягких тканей. Практическая онкология. 2004, т. 5, № 4, с. 237-242.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Coindre J.M., Terrier P., Guillou L. et al. Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas: a study of 1240 patients from the French Federation of Cancer Centers Sarcoma Group. Cancer. 2001, v. 91, p. 1914-1926.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Stoeckle E., Coindre J.M., Kind M. et al. Evaluating surgery quality in soft tissue sarcoma. Recent Results Cancer Res. 2009, v. 179, p. 229-242.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Mazanet R., Antman K. Sarcomas of soft tissues and bone. Cancer. 1991, v. 68, p. 463-473.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Bowden L., Booher R.J. The principle and techniques of resection of soft parts of sarcoma. Surgery. 1958, v. 44, p. 963-977.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Firth L.A. The relative roles of surgery and radiotherapy in the management of soft tissue sarcomas of adults. Clin. Radiol. 1979, v. 30, p. 155-159.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Simon M.A., Enneking W.F. The management of soft tissue sarcomas of the extremities. J. Bone loint Surg. 1976, v. 58, p. 317-327.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Enneking W.E., Spanier S.S., Malawer M.M. The effect of the anatomic setting on the results of surgical procedures for soft parts sarcoma of the thigh. Cancer. 1981, v. 47, p. 1005-1022.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Pollock R.E., Karnell L.H., Menck H.R. et al. The National Cancer Data base report on soft tissue sarcoma. Cancer. 1996, v. 78, p. 2247-2257.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Coindre J.M., Terrier P., Bui N.B. et al. Prognostic factors in adult patients with locally controlled soft tissue sarcoma. A study on 546 patients from the French Federation of Cancer Centers Sarcoma Group. J. Clin. Oncol. 1996, v. 14, p. 869-877.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Pisters P.W., Leung D.H., Woodruff J. et al. Analysis of prognostic factors in 1041 patients with localized soft tissue tumours of the extremities. J. Clin. Oncol. 1996, v. 14, p. 1679-1689.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Ravaud A., Bui N.B., Coindre J.M. etal. Prognostic variables for the selection of patients with operable soft tissue sarcomas to be considered in adjuvant chemotherapy trials. Br. J. Cancer. 1992, v. 66, p. 961-969.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Saddegh M.K., Lindholm J., Lundberg A. et al. Staging of soft tissue sarcomas. Prognostic analysis of clinical and pathological features. J. Bone loint Surg. 1992, v. 74, p. 495-500.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Bell R.S., O'Sullivan B., Liu F.F. et al. The surgical margin in soft tissue sarcoma. J. Bone loint Surg. 1989, v. 71, p. 370-375.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Mandard A.M., Petiot J.F., Marnay J. etal. Prognostic factors in soft tissue sarcomas. A multivariate analysis of 109 cases. Cancer. 1989, v. 63, p. 1437-1451.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Rydholm A., Berg N.O., Gullberg B.O. et al. Prognosis for soft-tissue sarcoma in the locomotor system. A retrospective population-based follow-up study of 237 patients. Acta Pathol. Microbiol. Immunol. Scand. 1984, v. 92, p. 375-386</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Markhede G., Angervall L., Stener B. A multivariate analysis of the prognosis after surgical treatment of malignant soft tissue sarcomas. Cancer. 1982, v. 49, p. 1721-1733.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Trojani M., Contesso G., Coindre J.M. et al. Soft-tissue sarcoma of adults: study of pathological prognostic variables and definition of a histopathological grading system. Int. J. Cancer. 1984, v. 33, p. 37-42.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Guillou L., Coindre J.M., Bonichon F. et al. Comparative study of the National Cancer Institute and French Federation of Cancer Centers Sarcoma Group grading systems in a population of 410 adult patients with oft tissue sarcoma. J. Clin. Oncol. 1997, v. 15, p. 350-362.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Coindre J.M., Trojani M., Contesso G. et al. Reproducibility of a histopathologic grading system for adult soft tissue sarcoma. Cancer. 1986, v. 58, p. 306-309.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Simon M.A., Enneking W.F. The management of soft tissue sarcomas of the extremities. J. Bone Joint Surg. 1976, v. 58, p. 317-327.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Cantin J., McNeer G.P, Clin F.С. et al. The problem of local recurrence after treatment of soft tissue sarcoma. Ann. Surg. 1968, v. 168, p. 47-53.</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Shiu M.H., Castro E.B., Hajdu S.I. et al. Surgical treatment of 297 soft tissue sarcomas of the lower extremity. Ann. Surg. 1975, v. 182, p. 597-602.</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Karakousis C.P., Emrich L.J., Rao U. et al. Feasibility of limb salvage and survival in soft tissue sarcomas. Cancer. 1986, v. 57, p. 484-491.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Rydholm A., Gustafson P., Röoser B. et al. Limb-sparing surgery without radiotherapy based on anatomic location of soft tissue sarcoma. J. Clin. Oncol. 1991, v. 9, p. 1757-1765.</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Gaynor J.J., Tan C.C., Casper E.S. et al. Refinement of clinicopathologic staging for localized soft tissue sarcoma of the extremity: a study of 423 adults. J. Clin. Oncol. 1992, v. 10, p.1317-1329.</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Trovik C.S., Bauer H.C., Alvegard Т.А. et al. Surgical margins, local recurrence and metastasis in soft tissue sarcomas: 559 surgically-treated patients from the Scandinavian Sarcoma Group Register. 2000, v. 36, No. 6, p. 710-716.</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Ruka W., Emrich L.J., Driscoll D.L. et al. Clinical factors and treatment parameters affecting prognosis in adult high-grade soft tissue sarcomas: a retrospective review of 267 cases. Eur. J. Surg. Oncol. 1989, v. 15, p. 411-423.</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Azzarelli A. Surgery in soft tissue sarcomas. Eur. J. Cancer. 1993, p. 618-623.</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>LeVay J., O'Sullivan В., Catton C. et al. Outcome and prognostic factors in soft tissue sarcoma in the adult. Int. J. Radiat. Oncol. Biol. Phys. 1993, v. 27, p. 1091-1099.</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Gustafson P. Soft tissue sarcoma. Epidemiology and prognosis in 508 patients. Acta Orthop. Scand. 1994, v. 65. p. 1-31.</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Keus R.B., Rutgers E.J., Ho G.H. et al. Limb-sparing therapy of extremity soft tissue sarcomas: treatment outcome and long-term functional results. Eur. J. Cancer. 1994, v. 30, p. 1459-1463.</mixed-citation></ref><ref id="B33"><label>33.</label><mixed-citation>Peiper M., Zurakowski D., Zornig C. Survival in primary soft tissue sarcoma of the extremities and trunk. Langenbecks Arch. Chir. 1997, v. 382, p. 203-208.</mixed-citation></ref><ref id="B34"><label>34.</label><mixed-citation>Bauer H., Trovik C., Alvegard T. et al. Monitoring referral and treatment in soft tissue sarcoma. Study based on 1851 patients from the Scandinavian Sarcoma Group register. Acta Orthop. Scand. 2001, v. 72, p. 150-159.</mixed-citation></ref><ref id="B35"><label>35.</label><mixed-citation>Stefanovski P., Bidoli E., de Paoli A. et al. Prognostic factors in soft tissue sarcomas: a study of 395 patients. Eur. J. Surg. Oncol. 2002, v. 28, p. 153-164.</mixed-citation></ref><ref id="B36"><label>36.</label><citation-alternatives><mixed-citation xml:lang="en">Eilber F.C., Rosen G., Nelson S.D. et al. High-grade extremity soft tissue sarcomas. Factors predictive of local recurrence and its effect on morbidity. Ann. Surg. 2003, v. 2, p. 218-226.</mixed-citation><mixed-citation xml:lang="ru">Eilber F.C., Rosen G., Nelson S.D. et al. High-grade extremity soft tissue sarcomas. Factors predictive of local recurrence and its effect on morbidity. Ann. Surg. 2003, v. 2, p. 218-226.</mixed-citation></citation-alternatives></ref><ref id="B37"><label>37.</label><mixed-citation>McKee M.D., Liu D.F, Brooks J.J. et al. The prognostic significance of margin width for extremity and trunk sarcoma. J. Surg. Oncol. 2004, v. 85, p. 68-76.</mixed-citation></ref><ref id="B38"><label>38.</label><mixed-citation>Dickinson I.C., Whitwell D.J., Battistuta D. et al. Surgical margin and its influence on survival in soft tissue sarcoma. ANZ. J. Surg. 2006, v. 76, p. 104-109.</mixed-citation></ref><ref id="B39"><label>39.</label><mixed-citation>Lindberg R.D., Martin R.G., Romsdahl M.M., Morton D.L. Conservative surgery and postoperative radiotherapy in 300 adults with soft tissue sarcomas. Cancer. 1981, v. 47, p. 2391-2397.</mixed-citation></ref><ref id="B40"><label>40.</label><mixed-citation>Avizonis V.N., Sause W.T., Menlove R.L. Utility of surgical margins in the radiotherapeutic management of soft tissue sarcomas. J. Surg. Oncol. 1990, v. 45, p. 85-90.</mixed-citation></ref><ref id="B41"><label>41.</label><mixed-citation>Stotter A.T., A'Hern R.P., Fisher С. et al. The influence of local recurrence of extremity soft tissue sarcoma on metastases and survival. Cancer. 1990, v. 65, p. 1119-1129.</mixed-citation></ref><ref id="B42"><label>42.</label><mixed-citation>Langlois D., Bey P., Luporsi E. et al. Radiothérapie des sarcomes des parties molles: place et résultats. Bull. Cancer Radiother. 1991, v. 78, p. 39-49.</mixed-citation></ref><ref id="B43"><label>43.</label><mixed-citation>Herbert S.H., Corn B.W., Solin L.J. et al. Limb-preserving treatment for soft tissue sarcomas of the extremities. The significance of surgical margins. Cancer. 1993, v. 72, p. 1230-1238.</mixed-citation></ref><ref id="B44"><label>44.</label><mixed-citation>Sadoski C., Suit H.D., Rosenberg A. et al. Preoperative radiation, surgical margins, and local control of extremity sarcomas of soft tissues. J. Surg. Oncol. 1993, v. 52, p. 223-230.</mixed-citation></ref><ref id="B45"><label>45.</label><mixed-citation>Zagars G.K., Ballo M.T., Pisters P.W. et al. Prognostic factors for patients with localized soft-tissue sarcoma treated with conservation surgery and radiation therapy. An analysis of 1225 patients. 2003, v. 5, No. 3, p. 739-747.</mixed-citation></ref><ref id="B46"><label>46.</label><mixed-citation>Khanfir K., Alzieu L., Terrier P. et al. Does adjuvant radiation therapy increase loco-regional control after optimal resection of soft-tissue sarcoma of the extremities? Eur. J. Cancer. 2003, v. 39, p. 1872-1880.</mixed-citation></ref><ref id="B47"><label>47.</label><mixed-citation>Gronchi A., Casali P.G., Mariani L. et al. Status of surgical margins and prognosis in adult soft tissue sarcomas of the extremities: a series of patients treated at a single institution. J. Clin. Oncol. 2005, v. 23, p. 96-104.</mixed-citation></ref><ref id="B48"><label>48.</label><mixed-citation>Koea J.B., Leung D., Lewis J.J., Brennan M.F Histopathologic type: an independent prognostic factor in primary soft tissue sarcoma of the extremity? Ann. Surg. Oncol. 2003, v. 10, p. 432-440.</mixed-citation></ref><ref id="B49"><label>49.</label><mixed-citation>Stojadinovic A., Leung D.H., Allen P. et al. Primary adult soft tissue sarcoma: time-dependent influence of prognostic variables. J. Clin. Oncol. 2002, v. 20, p. 4344-4352.</mixed-citation></ref><ref id="B50"><label>50.</label><mixed-citation>Stojadinovic A., Leung D.H., Hoos A. et al. Analysis of the prognostic significance of microscopic margin in 2,084 localized primary adult soft tissue sarcomas. Ann. Surg. 2002, v. 235, p. 424-434.</mixed-citation></ref><ref id="B51"><label>51.</label><mixed-citation>Stoeckle E., Gardet H., Coindre J.M. et al. Prospective evaluation of quality of surgery in soft tissue sarcoma. Eur. J. Surg. Oncol. 2006, v. 32, p. 1242-1248.</mixed-citation></ref><ref id="B52"><label>52.</label><mixed-citation>Kawaguchi N., Ahmed A. R., Matsumoto S. et al. The concept of curative margin in surgery forbone and soft tissue sarcoma. Clin. Orthop. 2004, v. 419, p. 165-172.</mixed-citation></ref><ref id="B53"><label>53.</label><mixed-citation>Gerrand C.H., Wunder J.S., Kandel R.A. et al. Classification of positive margins after resection of soft-tissue sarcoma of the limb predicts the risk of local recurrence. J. Bone Joint Surg. 2001, v. 83, p. 1149-1155.</mixed-citation></ref><ref id="B54"><label>54.</label><mixed-citation>Giuliano A.E., Eilber F.R. The rationale for planned reoperation after unplanned total excision of soft-tissue sarcomas. J. Clin. Oncol. 1985, v. 3p. 1344-1348.</mixed-citation></ref><ref id="B55"><label>55.</label><mixed-citation>Noria S., Davis A., Kandel R. et al. Residual disease following unplanned excision of soft-tissue sarcoma of an extremity. J. Bone Joint Surg. Am. 1996, v. 78, p. 650-655.</mixed-citation></ref><ref id="B56"><label>56.</label><mixed-citation>Hoshi M., Ieguchi M., Takami M. et al. Clinical problems after initial unplanned resection of sarcoma. Jpn. J. Clin. Oncol. 2008, v. 38, No. 10, p. 701-709.</mixed-citation></ref><ref id="B57"><label>57.</label><mixed-citation>Jemal A., Siegel R., Ward E. et al. Cancer statistics, 2007. CA Cancer J. Clin. 2007, v. 57, p. 43-66.</mixed-citation></ref><ref id="B58"><label>58.</label><mixed-citation>Wong C.K., Lam Y.L., So Y.C. et al. Management of extremity soft tissue sarcoma after unplanned incomplete resection: experience of a regional musculoskeletal tumour centre. Hong Kong Med. J. 2004, v. 10, p. 117-122.</mixed-citation></ref><ref id="B59"><label>59.</label><mixed-citation>Mankin H.J., Lange T.A., Spanier S.S. The hazards of biopsy in patients with malignant primary bone and soft tissue tumours. J. Bone Joint Surg. 1982, v. 64, p. 1121-1127.</mixed-citation></ref><ref id="B60"><label>60.</label><mixed-citation>Siebenrock K.A., Hertel R., Ganz R. Unexpected resection of soft-tissue sarcoma. More mutilating surgery, higher local recurrence rates, and obscure prognosis as consequences of improper surgery. Arch. Orthop. Trauma Surg. 2000, v. 120, p. 65-69.</mixed-citation></ref><ref id="B61"><label>61.</label><mixed-citation>Kaste S.C., Hill A., Conley L. et al. Magnetic resonance imaging after incomplete resection of soft tissue sarcoma. Clin. Orthop. Relat. Res. 2002, v. 397, p. 204-211.</mixed-citation></ref><ref id="B62"><label>62.</label><mixed-citation>Shapeero L.G., Vanel D., Verstraete K.L., Bloem J.L. Fast magnetic resonance imaging with contrast for soft tissue sarcoma viability. Clin. Orthop. Relat. Res. 2002, v. 397, p. 212-227.</mixed-citation></ref><ref id="B63"><label>63.</label><mixed-citation>Stojadinovic A., Leung D.H., Hoos A. et al. Analysis of the prognostic significance of microscopic margins in 2,084 localized primary adult soft tissue sarcomas. Ann. Surg. 2002, v. 235, p. 424-434.</mixed-citation></ref><ref id="B64"><label>64.</label><mixed-citation>Sugiura H., Takahashi M., Katagiri H. et al. Additional wide resection of malignant soft tissue tumors. Clin. Orthop. Relat. Res. 2002, v. 394, p. 201-210.</mixed-citation></ref><ref id="B65"><label>65.</label><mixed-citation>Fiore M., Casali P.G., Miceli R. et al. Prognostic effect of re-excision in adult soft tissue sarcoma of the extremity. Ann. Surg. Oncol. 2006, v. 13, p. 110-117.</mixed-citation></ref><ref id="B66"><label>66.</label><mixed-citation>Manoso M.W., Frassica D.A, Deune E.G., Frassica F.J. Outcomes of re-excision after unplanned excisions of soft-tissue sarcomas. J. Surg. Oncol. 2005, v. 91, p. 153-158.</mixed-citation></ref><ref id="B67"><label>67.</label><mixed-citation>Lewis J.J., Leung D., Espat J. et al. Effect of re-resection in extremity soft tissue sarcoma. Ann. Surg. 2000, v. 231, p. 655-663.</mixed-citation></ref><ref id="B68"><label>68.</label><mixed-citation>Ueda T., Yoshikawa H., Mori S. et al. Influence of local recurrence on the prognosis of soft-tissue sarcomas. J. Bone Joint. Surg. Br. 1997, v. 79, p. 553-557.</mixed-citation></ref><ref id="B69"><label>69.</label><mixed-citation>Peiper M., Zornig C., Schroder S. Re-excision of soft tissue sarcoma after inadequate initial operation. Br. J. Surg. 1995, v. 82, p. 278-279.</mixed-citation></ref><ref id="B70"><label>70.</label><mixed-citation>Kawaguchi N., Matumoto S., Manabe J. New method of evaluating the surgical margin and safety margin for musculoskeletal sarcoma, analysed on the basis of 457 surgical cases. J. Cancer Res. Clin. Oncol. 1995, v. 121, p. 555-563.</mixed-citation></ref><ref id="B71"><label>71.</label><mixed-citation>Chmell M.J., Schwartz H.S. Analysis of variables affecting wound healing after musculoskeletal sarcoma resections. J. Surg. Oncol. 1996, v. 61, p. 185-189.</mixed-citation></ref><ref id="B72"><label>72.</label><mixed-citation>Bujko K., Suit H.D., Springfield D.S., Convery K. Wound healing after preoperative radiation for sarcoma of soft tissues. Surg. Obstet Gynaecol. 1997, v. 176, p. 124-134.</mixed-citation></ref><ref id="B73"><label>73.</label><mixed-citation>Barwick W.J., Golgberg J.A., Scully S.P., Harrelson J.M. Vascularized tissue transfer for closure of irradiated wounds after soft tissue sarcoma resection. Ann. Surg. 1992, v. 216, No. 5, p. 591-595.</mixed-citation></ref><ref id="B74"><label>74.</label><mixed-citation>Bell R.S., O'Sullivan B., Davis A. et al. Functional outcomein patients treated with surgery and irradiation for soft tissue tumours. J. Surg. Oncol. 1991, v. 48, p. 224-231.</mixed-citation></ref><ref id="B75"><label>75.</label><mixed-citation>Cheng E.Y., Dusenbery K.E., Winters M.R., Thompson R.C. Soft tissue sarcomas: preoperative versus postoperative radiotherapy. J. Surg. Oncol. 1996, v. 61, p. 90-99.</mixed-citation></ref><ref id="B76"><label>76.</label><mixed-citation>Peat B.G., Bell R.S., Davis A. et al. Wound healing complications after soft tissue sarcoma surgery. Plastic. Reconstr. Surg. 1994, v. 93, No. 5, p. 980-987.</mixed-citation></ref><ref id="B77"><label>77.</label><mixed-citation>Исмаил-заде Р.С. Комплексное лечение местно-распространенных сарком мягких тканей конечностей. Вопр. онкологии. 1991, т. 37, № 4, с. 475-479.</mixed-citation></ref><ref id="B78"><label>78.</label><mixed-citation>Mankin H.J., Lange T.A., Spanier S.S. The hazards ofbiopsy in patients with malignant primary bone and soft tissue tumours. J. Bone Joint. Surg. 1982, v. 64, p. 1121-1127</mixed-citation></ref></ref-list></back></article>
