Bone and soft tissue sarcomas, tumors of the skinBone and soft tissue sarcomas, tumors of the skinСаркомы костей, мягких тканей и опухоли кожи2219-46142782-3687Publishing House ABV Press280TUMORS OF THE SKINОПУХОЛИ КОЖИSentinel lymph node biopsy in cutaneous melanomaБиопсия «сторожевых» лимфатических узлов при меланоме кожиKukushkinaM. N.КукушкинаМ. Н.
Russian Federation
KorovinS. I.КоровинС. И.
Russian Federation
SolodyannikovaO. I.СолодянниковаО. И.
Russian Federation
SukachG. G.СукачГ. Г.
Russian Federation
PalivetsA. Yu.ПаливецА. Ю.
Russian Federation
KovalchukE. N.КовальчукЭ. Н.
Russian Federation
SkorodaL. V.СкородаЛ. В.
Russian Federation
National Cancer InstituteНациональный институт рака1106201243394811012022Copyright ©; 2012, Kukushkina M.N., Korovin S.I., Solodyannikova O.I., Sukach G.G., Palivets A.Y., Kovalchuk E.N., Skoroda L.V.Copyright ©; 2012, Кукушкина М.Н., Коровин С.И., Солодянникова О.И., Сукач Г.Г., Паливец А.Ю., Ковальчук Э.Н., Скорода Л.В.2012Kukushkina M.N., Korovin S.I., Solodyannikova O.I., Sukach G.G., Palivets A.Y., Kovalchuk E.N., Skoroda L.V.Кукушкина М.Н., Коровин С.И., Солодянникова О.И., Сукач Г.Г., Паливец А.Ю., Ковальчук Э.Н., Скорода Л.В.https://creativecommons.org/licenses/by/4.0https://sarbon.abvpress.ru/jour/article/view/280

Today sentinel lymph node biopsy in cutaneous melanoma is a standard diagnostic procedure. The factors that have prognostic value for occurrence of micrometastases in regional lymph nodes are tumor thickness by Breslow, ulceration, level of invasion by Clark IV-V, the patient’s age. The presence or absence of metastases in «sentinel» lymph nodes is a significant prognostic factor for patients with primary malignant melanoma of the skin. The need for implementation of regional lymph node dissection in the presence of micrometastases in sentinel lymph nodes remains an open question and requires further investigation.

На сегодняшний день биопсия «сторожевых» лимфатических узлов при меланоме кожи является стандартной диагностической процедурой. Факторами, имеющими прогностическое значение для появления микрометастазов в регионарных лимфатических узлах, являются толщина опухоли по Breslow, ее изъязвление, уровень инвазии по Clark IV-V, возраст больного. наличие или отсутствие метастазов в «сторожевых» лимфатических узлах является достоверным прогностическим фактором для больных с первичной меланомой кожи. Вопрос о необходимости выполнения регионарной лимфодиссекции при наличии микрометастазов в «сторожевых» лимфатических узлах пока остается открытым и требует дальнейшего исследования. история внедрения биопсии «сторожевых» лимфатических узлов в клиническую практику

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