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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Bone and soft tissue sarcomas, tumors of the skin</journal-id><journal-title-group><journal-title xml:lang="en">Bone and soft tissue sarcomas, tumors of the skin</journal-title><trans-title-group xml:lang="ru"><trans-title>Саркомы костей, мягких тканей и опухоли кожи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2219-4614</issn><issn publication-format="electronic">2782-3687</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">315</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>BONE SARCOMAS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>САРКОМЫ КОСТЕЙ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Radiation-induced osteosarcoma of the mandible</article-title><trans-title-group xml:lang="ru"><trans-title>Радиоиндуцированная остеогенная саркома нижней челюсти</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kropotov</surname><given-names>M. A.</given-names></name><name xml:lang="ru"><surname>Кропотов</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>drkropotov@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Agabekyan</surname><given-names>G. O.</given-names></name><name xml:lang="ru"><surname>Агабекян</surname><given-names>Г. О.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>г. Москва</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Yakovleva</surname><given-names>L. P.</given-names></name><name xml:lang="ru"><surname>Яковлева</surname><given-names>Л. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Clinical Research Center. A.S.Loginova</institution></aff><aff><institution xml:lang="ru">ГБУЗ Московский клинический научный центр им. А.С. Логинова ДЗМ</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Federal	State	Budgetary	Institution «N.N.	Blokhin	National	Medical Research	Center of	Oncology» of the	Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-09-15" publication-format="electronic"><day>15</day><month>09</month><year>2017</year></pub-date><volume>9</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>8</fpage><lpage>13</lpage><history><date date-type="received" iso-8601-date="2022-01-15"><day>15</day><month>01</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-01-15"><day>15</day><month>01</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Kropotov M.A., Agabekyan G.O., Yakovleva L.P.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, Кропотов М.А., Агабекян Г.О., Яковлева Л.П.</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Kropotov M.A., Agabekyan G.O., Yakovleva L.P.</copyright-holder><copyright-holder xml:lang="ru">Кропотов М.А., Агабекян Г.О., Яковлева Л.П.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://sarbon.abvpress.ru/jour/article/view/315">https://sarbon.abvpress.ru/jour/article/view/315</self-uri><abstract xml:lang="en"><p>The article describes one of the most controversial topics of oncology – radiation-induced tumors, in particular, sarcomas of the head and neck region.Radiation therapy is one of the most important methods of treating malignant neoplasms in modern oncology as an independent variant (possibly in combination with chemotherapy) and as adjuvant treatment after the operation. however, with the improvement of the results of treatment of cancer patients, more attention is devote to the side effects and complications of radiotherapy. one of the most rare and late complications are radiation-induced tumors that develop in irradiated tissues after a certain latent period.</p></abstract><trans-abstract xml:lang="ru"><p>В статье описана одна из наиболее дискутабельных тем онкологии – радиоиндуцированные опухоли, в частности, саркомы области головы и шеи.Лучевая терапия является одним из важнейших методов лечения злокачественных новообразований в современной онкологии как в самостоятельном варианте (возможно в сочетании с химиотерапией), так и в качестве адъювантного лечения после операции.</p></trans-abstract><kwd-group xml:lang="en"><kwd>radiation-induced sarcoma</kwd><kwd>tumors of head and neck</kwd><kwd>secondary tumors</kwd><kwd>squamous cell carcinoma</kwd><kwd>mandible</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>радиоиндуцированные саркомы</kwd><kwd>опухоли головы и шеи</kwd><kwd>вторые опухоли</kwd><kwd>плоскоклеточный рак</kwd><kwd>нижняя челюсть</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. 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