Bone and soft tissue sarcomas, tumors of the skinBone and soft tissue sarcomas, tumors of the skinСаркомы костей, мягких тканей и опухоли кожи2219-46142782-3687Publishing House ABV Press360BONE SARCOMASСАРКОМЫ КОСТЕЙLow-grade central osteosarcoma. ReviewЦентральная остеосаркома с низким злокачественным потенциалом. Обзор литературыRogozhinD. V.РогожинД. В.
Russian Federation

Moscow

г. Москва

Pathol.777@mail.ruKonovalovD. M.КоноваловД. М.
Russian Federation

Moscow

г. Москва

TalalaevA. G.ТалалаевА. Г.
Russian Federation

Moscow

г. Москва

RoschinV. Yu.РощинВ. Ю.
Russian Federation

Moscow

г. Москва

BolshakovN. A.БольшаковН. А.
Russian Federation

Moscow

г. Москва

TikhonovaM. V.ТихоноваМ. В.
Russian Federation

Moscow

г. Москва

RemizovA. N.РемизовА. Н.
Russian Federation

Moscow

г. Москва

Russian Children’s Clinical HospitalФГБУ «Российская детская клиническая больница»Research Center of Pediatric Hematology, Oncology and ImmunologyФГБУ «Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Д. Рогачева»Russian Children’s Clinical HospitalФГБУ «Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Д. Рогачева»Research Center of Pediatric Hematology, Oncology and ImmunologyRussian Children’s Clinical Hospital221020168316212201202222012022Copyright ©; 2016, Rogozhin D.V., Konovalov D.M., Talalaev A.G., Roschin V.Y., Bolshakov N.A., Tikhonova M.V., Remizov A.N.Copyright ©; 2016, Рогожин Д.В., Коновалов Д.М., Талалаев А.Г., Рощин В.Ю., Большаков Н.А., Тихонова М.В., Ремизов А.Н.2016Rogozhin D.V., Konovalov D.M., Talalaev A.G., Roschin V.Y., Bolshakov N.A., Tikhonova M.V., Remizov A.N.Рогожин Д.В., Коновалов Д.М., Талалаев А.Г., Рощин В.Ю., Большаков Н.А., Тихонова М.В., Ремизов А.Н.https://creativecommons.org/licenses/by/4.0https://sarbon.abvpress.ru/jour/article/view/360

Low-grade central osteosarcoma is a rare subtype of intramedullary osteosarcoma (approximately 1% of all osteosarcomas) that characterized histologically by a spindle cell proliferation associated with trabecular bone formation, and is usually located in the long bones with a predilection for the distal femur and proximal tibia. It has the potential to recur, dedifferentiate, and metastasize subsequent to surgical treatment. Sometimes it is difficult to make a diagnosis and differentiate it with fibrous dysplasia and desmoplastic fibroma. In such cases, careful radiological interpretation is helpful. This tumor usually carries a good prognosis.

Центральная остеосаркома с низким потенциалом злокачественности – это интрамедуллярная злокачественная опухоль костей (составляет порядка 1% среди всех остеосарком), состоящая из веретеновидных неопластических клеток с наличием костного компонента (остеоида или костной ткани). Локализуется чаще всего в длинных трубчатых костях с преобладанием в дистальной части бедренной кости и проксимальной части большеберцовой кости. Может локально рецидивировать, подвергаться дедифференцировке или метастазировать после хирургического лечения. В некоторых случаях представляет сложности в дифференциальной диагностике с фиброзной дисплазией и десмопластической фибромой. Имеет хороший прогноз.

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