Bone and soft tissue sarcomas, tumors of the skinBone and soft tissue sarcomas, tumors of the skinСаркомы костей, мягких тканей и опухоли кожи2219-46142782-3687Publishing House ABV Press39BONE SARCOMASСАРКОМЫ КОСТЕЙThe role of novel prognostic factors in treatment of patient witn spine metastasesФакторы прогноза при метастатическом поражении позвоночника (Литературный обзор)KulagaA. V.КулагаА. В.
Russian Federation
roncspine@gmail.comMusaevE. R.МусаевЭ. Р.
Russian Federation
ValievA. K.ВалиевА. К.
Russian Federation
BorzovK. A.БорзовК. А.
Russian Federation
KabardaevR. M.КабардаевР. М.
Russian Federation
AlievM. D.АлиевМ. Д.
Russian Federation
FSBI «N.N. Blokhin National Medical Research Center of Oncology» оf the Health Ministry of RussiaФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России16082018103233016042021Copyright ©; 2018, Kulaga A.V., Musaev E.R., Valiev A.K., Borzov K.A., Kabardaev R.M., Aliev M.D.Copyright ©; 2018, Кулага А.В., Мусаев Э.Р., Валиев А.К., Борзов К.А., Кабардаев Р.М., Алиев М.Д.2018Kulaga A.V., Musaev E.R., Valiev A.K., Borzov K.A., Kabardaev R.M., Aliev M.D.Кулага А.В., Мусаев Э.Р., Валиев А.К., Борзов К.А., Кабардаев Р.М., Алиев М.Д.https://creativecommons.org/licenses/by/4.0https://sarbon.abvpress.ru/jour/article/view/39

It performed the analysis of literature data on assessing cancer prognosis possibilities in patients with spine metastases. Surgical intervention for metastatic spinal lesions is palliative, but the majority of patients who undergo local treatment of a given volume in combination with systemic therapy, have improved their quality of life. It is noted that the adequate determination and use of prognostic factors in clinical practice in the planning of surgical treatment helps to determine spinal surgery volume and assess the life expectancy in this patients. It described the developed prognosis systems (Tokuhashi, Sioutos, Tomita, Van der Linden, Bauer), and it is indicated that these scales differ depending on the parameters included in them and do not take into account the options for systemic treatment of a malignant disease and the presence of mutations in the tumor. It was concluded that the treatment of spinal metastases should be individualized and multidisciplinary, the rational choice of treatment and its scope should be based on a comprehensive assessment of anamnestic, clinical and prognostic data. Accurate assessment of the postoperative survival prognosis will improve the quality of medical care for this category of patients and achieve optimal indicators of quality of life.

Выполнен анализ литературных данных о возможностях оценки онкологического прогноза у больных с метастатическим поражением позвоночника. Хирургические вмешательства при метастатическом поражении позвоночника носят паллиативный характер, однако у большинства пациентов, прошедших локальное лечение того или иного объема в сочетании с системной терапией, отмечается улучшение качества жизни. Отмечено, что адекватное определение и использование прогностических факторов в клинической практике при планировании хирургического лечения помогает определить адекватный объем операции на позвоночнике и оценить предполагаемую продолжительность жизни у рассматриваемой категории пациентов. Рассмотрены разработанные к настоящему времени системы прогноза (Tokuhashi, Sioutos, Tomita, Van der Linden, Bauer), при этом указано, что эти шкалы различаются в зависимости от включенных в них параметров и не учитывают варианты системного лечения злокачественного заболевания и особенности опухолей, а именно наличия мутаций. Сделано заключение о том, что лечение метастатического поражения позвоночника должно быть индивидуализированным и мультидисциплинарным, рациональный выбор метода лечения и его объем должны основываться на комплексной оценке анамнестических, клинических и прогностических данных. Точная оценка прогноза послеоперационной выживаемости позволит улучшить качество медицинской помощи данной категории пациентов и достичь оптимальных показателей качества жизни.

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