Bone and soft tissue sarcomas, tumors of the skinBone and soft tissue sarcomas, tumors of the skinСаркомы костей, мягких тканей и опухоли кожи2219-46142782-3687Publishing House ABV Press418SOFT TISSUE SARCOMASСАРКОМЫ МЯГКИХ ТКАНЕЙThe combined treatment of locally advanced soft tissue sarcomas with the use of local hyperthermiaКомбинированное лечение местно-распространенных сарком мягких тканей с применением локальной гипертермииZubarevA. L.ЗубаревА. Л.
Russian Federation

Obninsk

г. Обнинск

dr-alzubarev@yandex.ruKurilchikA. A.КурильчикА. А.
Russian Federation

Obninsk

г. Обнинск

KurpeshevO. K.КурпешевО. К.
Russian Federation

Obninsk

г. Обнинск

StarodubtcevA. L.СтародубцевА. Л.
Russian Federation

Obninsk

г. Обнинск

IvanovV. E.ИвановВ. Е.
Russian Federation

Obninsk

г. Обнинск

Medical Radiological Research CenterМРНЦ им. А.Ф. Цыба – филиал ФГБУ «НМИРЦ» Минздрава России23042015727112301202223012022Copyright ©; 2015, Zubarev A.L., Kurilchik A.A., Kurpeshev O.K., Starodubtcev A.L., Ivanov V.E.Copyright ©; 2015, Зубарев А.Л., Курильчик А.А., Курпешев О.К., Стародубцев А.Л., Иванов В.Е.2015Zubarev A.L., Kurilchik A.A., Kurpeshev O.K., Starodubtcev A.L., Ivanov V.E.Зубарев А.Л., Курильчик А.А., Курпешев О.К., Стародубцев А.Л., Иванов В.Е.https://creativecommons.org/licenses/by/4.0https://sarbon.abvpress.ru/jour/article/view/418

117 patients with locally advanced STS treated in MRRC were analyzed. In group 1 were included 72 patients who received preoperative thermo-chemo-radiotherapy (ТCRТ) and surgery (S). The group 2 consisted of 45 patients treated with preoperative chemo-radiotherapy (CRТ) followed by S too. The locoregional-recurrence-free-survival (LRFS), metastasis-free survival and overall survival rates (93, 74, 88,5%) at 5 years were higher in groups with ТCRТ compared to the CRT (72,5, 59, 63%). Local hyperthermia didn’t increase an incidence of postoperative complications.

В МРНЦ были пролечены 117 больных местно-распространенными саркомами мягких тканей. Больные были распределены в группы по виду лечения. В первую были включены 72 пациента, которым провели предоперационную термохимиолучевую терапию (ТХЛТ) и хирургическое вмешательство. Вторую группу составили 45 пациентов, получившие химиолучевую терапию (ХЛТ) с последующей операцией. Показатели пятилетней безрецидивной, безметастатической и общей выживаемости оказались выше в группе с ТХЛТ (93, 74, 88,5%) в сравнении с группой ХЛТ (72,5, 59, 63%). Применение локальной гипертермии не увеличило количество послеоперационных осложнений. 

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