Bone and soft tissue sarcomas, tumors of the skinBone and soft tissue sarcomas, tumors of the skinСаркомы костей, мягких тканей и опухоли кожи2219-46142782-3687Publishing House ABV Press435SOFT TISSUE SARCOMASСАРКОМЫ МЯГКИХ ТКАНЕЙIsoleted limb regional perfusion in the combined treatment of patients with soft tissue sarcomas of the limbsИзолированная регионарная перфузия в комбинированном лечении пациентов с саркомами мягких тканей конечностейPetrochenkoN. S.ПетроченкоН. С.
Russian Federation

Moscow

г. Москва

petrochenko_nikolyy@rambler.ruN.N. Blokhin Russian Cancer Research CenterФГБНУ «Российский онкологический научный центр им. Н.Н. Блохина»230120157126312301202223012022Copyright ©; 2015, Petrochenko N.S.Copyright ©; 2015, Петроченко Н.С.2015Petrochenko N.S.Петроченко Н.С.https://creativecommons.org/licenses/by/4.0https://sarbon.abvpress.ru/jour/article/view/435

Soft tissue sarcoma (STS) – a heterogeneous group of tumors, which includes about 50 subtypes. generally STS are located on the extremities. The aim of the study is to analyze the possibility of using of isolated regional perfusion of extremities in the treatment of soft tissue sarcomas. According to major studies, the percentage of responses after the ILP is 70%, while a complete response develops in 20% of cases. Despite numerous studies and their optimistic results, the problem of the treatment of locally common extremity soft tissue sarcomas has not been fully resolved. To increase the efficiency of the ILP with melphalan and its wider use in the practice of specialized clinics the basic parameters of its implementation must be clearlyworked out, a patient selection criteria for integrated and combined treatment with the use of the ILP must be clearly formed.

Саркомы мягких тканей (СМТ) – гетерогенная группа опухолей, в которую включено около 50 подтипов. в большинстве случаев СМТ локализуются на конечностях. целью исследования является анализ возможностей применения метода изолированной регионарной перфузии конечностей в лечении сарком мягких тканей. по данным крупных исследований, доля ответов после ИРП составляет 70%, в то время как полный ответ развивается в 20% случаев. Несмотря на многочисленные исследования, их довольно оптимистические результаты, проблема лечения местнораспространенных сарком мягких тканей конечностей до конца не решена. Для увеличения эффективности ИРП с мелфаланом и более широкого ее применения в практике специализированных клиник необходимо четко отработать основные параметры ее проведения, четко сформировать критерии отбора пациентов к комплексному и комбинированному лечению с применением ИРП.

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