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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Bone and soft tissue sarcomas, tumors of the skin</journal-id><journal-title-group><journal-title xml:lang="en">Bone and soft tissue sarcomas, tumors of the skin</journal-title><trans-title-group xml:lang="ru"><trans-title>Саркомы костей, мягких тканей и опухоли кожи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2219-4614</issn><issn publication-format="electronic">2782-3687</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">480</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>BONE SARCOMAS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>САРКОМЫ КОСТЕЙ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Giant cell tumor of the bone</article-title><trans-title-group xml:lang="ru"><trans-title>Гигантоклеточная опухоль кости</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bludov</surname><given-names>A. B.</given-names></name><name xml:lang="ru"><surname>Блудов</surname><given-names>А. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>г. Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nered</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Неред</surname><given-names>А. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>г. Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zamogilnaya</surname><given-names>Ya. A.</given-names></name><name xml:lang="ru"><surname>Замогильная</surname><given-names>Я. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>г. Москва</p></bio><email>yzamogilnaya@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kochergina</surname><given-names>N. V.</given-names></name><name xml:lang="ru"><surname>Кочергина</surname><given-names>Н. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Moscow</p></bio><bio xml:lang="ru"><p>г. Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">FGBU N.N. Blokhin Russian Cancer Research Center</institution></aff><aff><institution xml:lang="ru">ФГБУ «Российский онкологический научный центр им. Н.Н. Блохина» РАМН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-01-27" publication-format="electronic"><day>27</day><month>01</month><year>2014</year></pub-date><volume>6</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>16</fpage><lpage>34</lpage><history><date date-type="received" iso-8601-date="2022-01-27"><day>27</day><month>01</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-01-27"><day>27</day><month>01</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Bludov A.B., Nered A.S., Zamogilnaya Y.A., Kochergina N.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, Блудов А.Б., Неред А.С., Замогильная Я.А., Кочергина Н.В.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Bludov A.B., Nered A.S., Zamogilnaya Y.A., Kochergina N.V.</copyright-holder><copyright-holder xml:lang="ru">Блудов А.Б., Неред А.С., Замогильная Я.А., Кочергина Н.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://sarbon.abvpress.ru/jour/article/view/480">https://sarbon.abvpress.ru/jour/article/view/480</self-uri><abstract xml:lang="en"><p>Giant cell tumour (GCT) is frequently diagnosed primary bone tumor. GCT histogenesis remains still unknown. This type of primary bone tumor classified in separate group and represents giant cell tumor with typical structure (benign GCT) and with less occurred giant cell tumor with atypical structure (malignancy in GCT). Radiology diagnostic methods are particular valuable in differential diagnosis of this tumor, because even plain radiography reveals GCT with a high accuracy.</p></abstract><trans-abstract xml:lang="ru"><p>Представлен обзор литературы, посвященный классификации, эпидемиологии, клиническому течению, морфологии и лучевой диагностике гигантоклеточной опухоли кости (ГКО). ГКО – достаточно часто встречаемая первичная опухоль кости, гистогенез которой остается невыясненным. Этот тип опухоли выделен в отдельную группу и представлен гигантоклеточной опухолью типичного строения и гораздо реже встречаемой злокачественной формой нетипичного строения. Методы лучевой диагностики играют особую роль в дифференциальной диагностике этого процесса, так как даже на этапе рутинной рентгенографии правильный диагноз может быть установлен с высокой точностью.</p></trans-abstract><kwd-group xml:lang="en"><kwd>giant cell tumor</kwd><kwd>malignancy in giant cell tumour</kwd><kwd>radiology</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>гигантоклеточная опухоль</kwd><kwd>злокачественная форма гигантоклеточной опухоли</kwd><kwd>лучевая диагностика</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Sung H.W., Kuo W.P., Chai Y.B., Liu C.C., Li S.M. Giant cell tumor of bone: analysis of two hundred and eight cases in Chinese patients. J. Bone Joint. Surg. [Am.] 1982, v. 64, p. 755-761.</mixed-citation><mixed-citation xml:lang="ru">Sung H.W., Kuo W.P., Chai Y.B., Liu C.C., Li S.M. 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