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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Bone and soft tissue sarcomas, tumors of the skin</journal-id><journal-title-group><journal-title xml:lang="en">Bone and soft tissue sarcomas, tumors of the skin</journal-title><trans-title-group xml:lang="ru"><trans-title>Саркомы костей, мягких тканей и опухоли кожи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2219-4614</issn><issn publication-format="electronic">2782-3687</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">605</article-id><article-id pub-id-type="doi">10.17650/2219-4614-2023-15-2-13-17</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Soft tissue sarcomas of the hand and foot: characteristics of progression and main surgical approaches</article-title><trans-title-group xml:lang="ru"><trans-title>Саркомы мягких тканей кисти и стопы: особенности течения и основные хирургические подходы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4965-5799</contrib-id><name-alternatives><name xml:lang="en"><surname>Gribkova</surname><given-names>E. I.</given-names></name><name xml:lang="ru"><surname>Грибкова</surname><given-names>Е. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Elizaveta I. Gribkova.</p><p>Bld. 2, 8 Trubetskaya St., Moscow 119991</p></bio><bio xml:lang="ru"><p>Грибкова Елизавета Игоревна.</p><p>119991 Москва, ул. Трубецкая, 8, стр. 2</p></bio><email>gribkovaei@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1241-3019</contrib-id><name-alternatives><name xml:lang="en"><surname>Musaev</surname><given-names>E. R.</given-names></name><name xml:lang="ru"><surname>Мусаев</surname><given-names>Э. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Bld. 2, 8 Trubetskaya St., Moscow 119991</p></bio><bio xml:lang="ru"><p>119991 Москва, ул. Трубецкая, 8, стр. 2</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО Первый Московский государственный медицинский университет имени И.М. Сеченова Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-07-01" publication-format="electronic"><day>01</day><month>07</month><year>2023</year></pub-date><volume>15</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>13</fpage><lpage>17</lpage><history><date date-type="received" iso-8601-date="2023-04-15"><day>15</day><month>04</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-07-01"><day>01</day><month>07</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Gribkova E.I., Musaev E.R.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Грибкова Е.И., Мусаев Э.Р.</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Gribkova E.I., Musaev E.R.</copyright-holder><copyright-holder xml:lang="ru">Грибкова Е.И., Мусаев Э.Р.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://sarbon.abvpress.ru/jour/article/view/605">https://sarbon.abvpress.ru/jour/article/view/605</self-uri><abstract xml:lang="en"><p>Soft tissue sarcomas of the hand and foot comprise a rare subgroup of mesenchymal tumors with more favorable oncological prognosis. For this type of tumors, several options of surgical treatment exist depending on histological subtype, size and local tumor advancement. Additionally, due to significant functional load on the distal parts of the limbs, surgical techniques for treatment of these patients have specific characteristics. However, publications on progression characteristics and prognosis of soft tissue sarcomas of the hand and foot are lacking.</p><p>This review describes soft tissue sarcomas of the hand and foot and analyzes surgical techniques for treatment of patients with this type of tumor.</p></abstract><trans-abstract xml:lang="ru"><p>Саркомы мягких тканей кисти и стопы представляют собой редкую подгруппу мезенхимальных опухолей с более благоприятным онкологическим прогнозом. Для данного вида новообразований существуют несколько опций хирургического лечения в зависимости от гистологического подтипа, размеров и местного распространения опухоли. Кроме того, в связи со значительной функциональной нагрузкой на дистальные отделы конечностей хирургические методы лечения пациентов с такими опухолями имеют особенности. Публикаций же, посвященных особенностям течения и прогнозу сарком мягких тканей кисти и стопы, немного.</p><p>В данном обзоре представлена характеристика сарком мягких тканей кисти и стопы, а также анализируются методы хирургического лечения пациентов с этим видом опухолей.</p></trans-abstract><kwd-group xml:lang="en"><kwd>soft tissue sarcomas</kwd><kwd>hand</kwd><kwd>foot</kwd><kwd>amputation</kwd><kwd>functional outcome</kwd><kwd>oncological outcome</kwd><kwd>oncology</kwd><kwd>surgery</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>саркомы мягких тканей</kwd><kwd>кисть</kwd><kwd>стопа</kwd><kwd>ампутация</kwd><kwd>функциональный исход</kwd><kwd>онкологический исход</kwd><kwd>онкология</kwd><kwd>хирургия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Sbaraglia M., Bellan E., Dei Tos A.P. The 2020 WHO classification of soft tissue tumours: news and perspectives. Pathologica 2020;113(2): 70–84. no. 2. DOI: 10.32074/1591-951X-213</mixed-citation></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Malignant neoplasms in Russia in 2020 (morbidity and mortality). Ed. by A.D. Kaprin, V.V. Starinsky, A.O. Shakhzadova. Moscow: P.A. Herzen Moscow State Medical Research Institute – branch of the Federal State Budgetary Institution “NMIC of Radiology” of the Ministry of Health of Russia, 2021</mixed-citation><mixed-citation xml:lang="ru">Злокачественные новообразования в России в 2020 году (заболеваемость и смертность). Под ред. А.Д. Каприна, В.В. Старинского, А.О. Шахзадовой. М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава России, 2021.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Mattei J.C., Brouste V., Terrier P. et al. Distal extremities soft tissue sarcomas: are they so different from other limb localizations? J Surg Oncol 2019;119(4):479–88. DOI: 10.1002/jso.25359</mixed-citation><mixed-citation xml:lang="ru">Mattei J.C., Brouste V., Terrier P.. et al. Distal extremities soft tissue sarcomas: are they so different from other limb localizations? J Surg Oncol 2019;119(4):479–88. DOI: 10.1002/jso.25359</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><mixed-citation>Walker M.J., Wood D.K., Briele H.A. et al. Soft tissue sarcomas of the distal extremities. Surgery 1986;99(4):392–8.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Farzaliyev F., Steinau H.-U., Ringet A. al. Classic type of epithelioid sarcoma of the distal upper extremity: clinical and oncological characteristics. Hand 2022;15589447221075745. DOI: 10.1177/15589447221075745</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Paral K.M., Petronic-Rosic V. Acral manifestations of soft tissue tumors. Clin Dermatol 2017;35(1):85–98. DOI: 10.1016/j.clindermatol.2016.09.012</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Dean B.J.F., Branford-White H., Giele H. et al. Management and outcome of acral soft-tissue sarcomas. Bone Joint J 2018;100-B(11):1518–23. DOI: 10.1302/0301-620X.100B11.BJJ-2018-0301.R1</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Harati K., Kirchhoff P., Behr B. et al. Soft tissue sarcomas of the distal lower extremities: a single-institutional analysis of the prognostic significance of surgical margins in 120 patients. Oncol Rep 2016;36(2):863–70. DOI: 10.3892/or.2016.4862</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Kim Y.J.. Song S.Y., Choiet W. al. Postoperative radiotherapy after limb-sparing surgery for soft-tissue sarcomas of the distal extremities. Anticancer Res 2016;36(9):4825–31. DOI: 10.21873/anticanres.11044</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Bishop A.J., Zagars G.K., Moon B.S. et al. Combined limb-sparing surgery and radiation therapy to treat sarcomas of the hands and feet: long-term cancer outcomes and morbidity. Int J Radiat Oncol Biol Phys 2015;92(5):1060–8. DOI: 10.1016/j.ijrobp.2015.04.022</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Pradhan A., Cheung Y.C., Grimer R.J. et al. Soft-tissue sarcomas of the hand oncological outcome and prognostic factors. J Bone Joint Surg Br 2008;90(2):209–14. DOI: 10.1302/0301-620X.90B2</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Mcphee M., Mcgrath B.E., Zhang P. et al. Soft tissue sarcoma of the hand. J Hand Surg Am 1999;24(5):1001–7. DOI: 10.1053/jhsu.1999.1001</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Houdek M.T., Beahrs T.R., Wyles C.C. et al. What factors are predictive of outcome in the treatment of soft tissue sarcomas of the foot and ankle? Foot Ankle Spec 2017;10(1):12–9. DOI: 10.1177/1938640016666925</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Lin P.P., Volkan B., Gusel P., Pisters P.W.T. et al. Surgical management of soft tissue sarcomas of the hand and foot. Cancer 2002;95(4):852–61. DOI: 10.1002/cncr.10750</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Trevino M., Moorthy C., Kafchinski L., Bustamante D. Foot plantar soft tissue malignant myoepithelioma tumor: case report and review of the literature. Clin Imaging;2020;61:90–4. DOI: 10.1016/j.clinimag.2019.11.014</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Saab-Chalhoub M.W., Al-Rohil R.N. Low-grade fibromyxoid sarcoma of acral sites: case report and literature review. J Cutan Pathol 2019;46(4):271–6. DOI: 10.1111/cup.13413</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Boc S.F., Das-Wattley S., Roberts E. Synovial sarcoma arising in the foot: case report. J Foot Ankle Surg 2011;50(1):117–21. DOI: 10.1053/j.jfas.2010.10.010</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Taranto J., Havlat M.F. Synovial sarcoma of the digits: a case report of an unplanned excision. J Foot and Ankle Surg 2018:57(2):388–92. DOI: 10.1053/j.jfas.2017.07.017</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Racz R., Belczyk R., Williams R.P.et al. Synovial sarcoma of the foot: a case report. J Am Podiatr Med Assoc 2010;100(3):216–9. DOI: 10.7547/1000216</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Matsuo T., Sugita T., Shimose S. et al. Liposarcoma arising in the foot: a case report. Case Rep Med 2009;2009:1–2. DOI: 10.1155/2009/630203</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Yu N.Z., Cheng F., Jin H.T. et al. Synovial sarcoma of the foot: a case report. Orthop Surg 2010;2(4):319–22. DOI: 10.1111/j.1757-7861.2010.00108.x</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Bekarev M., Elsinger E.C., Villanueva-Siles E. et al. Synovial sarcoma of the foot. J of Foot Ankle Surg 2013;52(4):513–7. DOI: 10.1053/j.jfas.2013.03.012</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Haight J., Caprioli R., Esposito M. et al. Synovial sarcoma involving the calcaneus and plantar compartment of the foot: a case report. J Foot and Ankle Surg 2010;49(4):398. DOI: 10.1053/j.jfas.2010.04.003</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Kaddu S., Wolf I., Horn M., Kerl H. Epithelioid sarcoma with angiomatoid features: Report of an unusual case arising in an elderly patient within a burn scar. J Cutan Pathol 2008;35(3):324–8. DOI: 10.1111/j.1600-0560.2007.00802.x</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Maia D.C.C., Bastos T.C., Francesconi F. et al. Poorly differentiated synovial sarcoma in the wrist – case report. An Bras Dermatol 2014;89(5):816–8. DOI: 10.1590/abd1806-4841.20143015</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Serinelli S., Gitto L., Zaccarini D.J. Synovial sarcoma of the hand-wrist: a case report and review of the literature. J Med Case Rep 2021;15(1):12. 2021. DOI: 10.1186/s13256-020-02613-4</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Sepetys G., Jakutis N. Soft-tissue sarcoma of the arm – an oncosurgical and reconstructive challenge: a case report. Nigeri J Clin Pract 2022;25(10):1766–8. DOI: 10.4103/njcp.njcp_215_22</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Ferguson P.C. Surgical considerations for management of distal extremity soft tissue sarcomas. Curr Opin Oncol 2005;17(4):366–9. DOI: 10.1097/01.cco.0000166651.38417.c8</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Zeytoonjian T., Mankin H.J., Gebhardt M.C., Hornicek F.J. Distal lower extremity sarcomas: frequency of occurrence and patient survival rate. Foot Ankle Int 2004;25(5):325–30. DOI: 10.1177/107110070402500509</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Deshmukh R., Mankin H.J., Singer S. Synovial sarcoma: the importance of size and location for survival. Clin Orthop 2004;419:155–61. DOI: 10.1097/01.blo.0000111887.82016.b0</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Salipas A., Dowsey M.M., May D., Choong P.F.M. “Beware the lump in the foot!”: predictors of recurrence and survival in bone and softtissue sarcomas of the foot and ankle. ANZ J Surg 2014;84(7–8):533–8. DOI: 10.1111/ans.12593</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Walling A.K., Gasser S.I. Soft-tissue and bone tumors about the foot and ankle. Clin Sports Med 1994;13(4):909–38.</mixed-citation></ref><ref id="B33"><label>33.</label><mixed-citation>McKee M.D., Liu D.F., Brooks J.J. et al. The prognostic significance of margin width for extremity and trunk sarcoma. J Surg Oncol 2004;85(2): 68–76. DOI: 10.1002/jso.20009</mixed-citation></ref><ref id="B34"><label>34.</label><mixed-citation>Biau D.J., Ferguson P.C., Chung P. et al. Local recurrence of localized soft tissue sarcoma: a new look at old predictors. Cancer 2012;118(23): 5867–77. DOI: 10.1002/cncr.27639</mixed-citation></ref><ref id="B35"><label>35.</label><mixed-citation>Ring A., Kirchhoff P., Goertz O.. et al. Reconstruction of soft-tissue defects at the foot and ankle after oncological resection. Front Surg 2016;3:15. DOI: 10.3389/fsurg.2016.00015</mixed-citation></ref><ref id="B36"><label>36.</label><mixed-citation>De Blacam C., Colakoglu S., Ogunleye A.A. et al. Risk factors associated with complications in lower-extremity reconstruction with the distally based sural flap: a systematic review and pooled analysis. J Plastic Reconstr Aesthetic Surg 2014;67(5):607–16. DOI: 10.1016/j.bjps.2014.01.044</mixed-citation></ref><ref id="B37"><label>37.</label><mixed-citation>Cassidy R.J., Indelicato D.J., Gibbs C.P. et al. Function preservation after conservative resection and radiotherapy for soft-tissue sarcoma of the distal extremity: utility and application of the Toronto Extremity Salvage Score (TESS). Am J Clin Oncol 2016;39(6):600–3. DOI: 10.1097/COC.0000000000000107</mixed-citation></ref><ref id="B38"><label>38.</label><mixed-citation>Kozawa E., Nishida Y., Nakashima H. et al. Foot sarcomas: factors affecting oncological and functional outcomes. Oncol Lett 2012;3(1):82–8. DOI: 10.3892/ol.2011.427</mixed-citation></ref><ref id="B39"><label>39.</label><mixed-citation>NCCN Guidelines Version 2.2023 Soft Tissue Sarcoma. 2003. Available at: https://www.nccn.org/guidelines/guidelines-detail?category=1&amp;id=1464.</mixed-citation></ref><ref id="B40"><label>40.</label><mixed-citation>Kandel R., Coakley N., Werier J. et al. Surgical margins and handling of soft-tissue sarcoma in extremities: a clinical practice guideline. Current Oncol 2013;20(3):e247–54. DOI: 10.3747/co.20.1308</mixed-citation></ref><ref id="B41"><label>41.</label><mixed-citation>Gerrand C.H., Wunder J.S., Kandel R.A. et al. The influence of anatomic location on functional outcome in lower-extremity soft-tissue sarcoma. Ann Surg Oncol 2004;11(5):476–82. DOI: 10.1245/ASO.2004.07.016</mixed-citation></ref><ref id="B42"><label>42.</label><mixed-citation>Kim J.Y., Youssef A., Subramanian V. et al. Upper extremity reconstruction following resection of soft tissue sarcomas: a functional outcomes analysis. Ann Surg Oncol 2004;11(10):921–7. DOI: 10.1245/ASO.2004.06.026</mixed-citation></ref></ref-list></back></article>
