Bone and soft tissue sarcomas, tumors of the skinBone and soft tissue sarcomas, tumors of the skinСаркомы костей, мягких тканей и опухоли кожи2219-46142782-3687Publishing House ABV Press64610.17650/2219-4614-2024-16-1-34-50REVIEWSОБЗОРНЫЕ СТАТЬИParaneoplastic dermatosis in pediatric and adult patientsПаранеопластические дерматозы у детей и взрослыхhttps://orcid.org/0000-0003-2252-8570MurashkinN. N.МурашкинН. Н.
Russian Federation

1 Bld., 2 Lomonosovsky Prospekt, Moscow 119991

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121359 Москва, ул. Маршала Тимошенко, 19, стр. 1А

https://orcid.org/0000-0002-1469-2365ValievT. T.ВалиевТ. Т.
Russian Federation

Timur Teimurazovich Valiev

2 Bld., 8 Trubetskaya St., Moscow 119991

24 Kashirskoye Shosse, Moscow 115522

Тимур Теймуразович Валиев

119991 Москва, ул. Трубецкая, 8, стр. 2

115522 Москва, Каширское шоссе, 24

timurvaliev@mail.ruhttps://orcid.org/0000-0001-5911-553XBelyshevaT. S.БелышеваТ. С.
Russian Federation

24 Kashirskoye Shosse, Moscow 115522

115522 Москва, Каширское шоссе, 24

https://orcid.org/0000-0002-0081-0981IvanovR. A.ИвановР. А.
Russian Federation

1 Bld., 2 Lomonosovsky Prospekt, Moscow 119991

119991 Москва, Ломоносовский проспект, 2, стр. 1

https://orcid.org/0000-0001-9557-3685SofronovD. I.СофроновД. И.
Russian Federation

24 Kashirskoye Shosse, Moscow 115522

115522 Москва, Каширское шоссе, 24

https://orcid.org/0000-0001-8443-8816RyabukhinaYu. E.РябухинаЮ. Е.
Russian Federation

111 1st Uspenskoe Shosse, Lapino Village, Odinrsovsky Dst., Moscow Region 143081

143081 Московская обл., Одинцовсикй р-н, д. Лапино, 1-е Успенское шоссе, 111

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Russian Federation

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https://orcid.org/0000-0003-1564-424XZeynalovaP. A.ЗейналоваП. А.
Russian Federation

2 Bld., 8 Trubetskaya St., Moscow 119991

111 1st Uspenskoe Shosse, Lapino Village, Odinrsovsky Dst., Moscow Region 143081

119991 Москва, ул. Трубецкая, 8, стр. 2

143081 Московская обл., Одинцовсикй р-н, д. Лапино, 1-е Успенское шоссе, 111

National Medical Research Center of Childrens Health, Ministry of Health of RussiaФГАУ «Национальный медицинский исследовательский центр здоровья детей» Минздрава РоссииI.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaФГАОУ ВО Первый Московский медицинский университет им. И.М. Сеченова Минздрава РоссииCentral State Medical Academy, Administrate of the President of Russian FederationФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента РФN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава РоссииClinical Hospital “Lapino”Клинический госпиталь «Лапино»Yaroslavl State Medical University, Ministry of Health of RussiaФГБОУ ВО «Ярославский государственный медицинский университет» Минздрава России0804202416134500804202408042024Copyright ©; 2024, Murashkin N.N., Valiev T.T., Belysheva T.S., Ivanov R.A., Sofronov D.I., Ryabukhina Y.E., Savelyeva M.I., Zeynalova P.A.Copyright ©; 2024, Мурашкин Н.Н., Валиев Т.Т., Белышева Т.С., Иванов Р.А., Софронов Д.И., Рябухина Ю.Е., Савельева М.И., Зейналова П.А.2024Murashkin N.N., Valiev T.T., Belysheva T.S., Ivanov R.A., Sofronov D.I., Ryabukhina Y.E., Savelyeva M.I., Zeynalova P.A.Мурашкин Н.Н., Валиев Т.Т., Белышева Т.С., Иванов Р.А., Софронов Д.И., Рябухина Ю.Е., Савельева М.И., Зейналова П.А.https://creativecommons.org/licenses/by/4.0https://sarbon.abvpress.ru/jour/article/view/646

Clinical, morpho-immunological and cytogenetic characteristics of malignancies are very polymorphic. And no less heterogeneous are paraneoplastic skin presentations arising before malignant tumour manifestation and/or proceeding in parallel. In the current literature review the most common paraneoplastic dermatosis are presented: pyoderma gangrenosa, dermatomyositis, paraneoplastic pemphigus, pityriasis rubra pilaris, Bazex syndrome, necrolytic migratory erythema, ptyriasis rotunda, Sweet syndrome. It is provided modern concepts in pathogenesis, clinical features and treatment approaches.

Клиническая, морфо-иммунологическая и цитогенетическая характеристика злокачесвенных опухолей крайне полиморфна. Не менее разнообразны и паранеопластические кожные проявления, возникающие до манифестации злокачественного новообразования и/или протекающие параллельно с ним. В настоящем обзоре представлены наиболее часто встречающиеся паранеопластические дерматозы: гангренозная пиодермия, дерматомиозит, паранеопластическая пузырчатка, красный волосяной лишай, синдром Базекса, некролитическая мигрирующая эритема, лишай ротонда и синдром Свита. С современных позиций освещены механизмы их развития, клинические проявления и подходы к терапии.

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