Bone and soft tissue sarcomas, tumors of the skinBone and soft tissue sarcomas, tumors of the skinСаркомы костей, мягких тканей и опухоли кожи2219-46142782-3687Publishing House ABV Press79BONE SARCOMASСАРКОМЫ КОСТЕЙSpinal metastases: current trends at solving problemsМетастатические поражения позвоночника. Современные аспекты диагностики и леченияIvlievD. S.ИвлиевД. С.
Russian Federation
ivlievdenis95@gmail.comLyulinS. V.ЛюлинС. В.
Russian Federation
BalaevP. I.БалаевП. И.
Russian Federation
Federal State Budget Institution «Federal Center of Traumatology, Orthopedics and Endoprosthetics» of the Ministry of Health of the Russian FederationФедеральное государственное бюджетное учреждение «Федеральный центр травматологии, ортопедии и эндопротезирования» Министерства здравоохранения Российской Федерации (г. Смоленск)Federal State Budget Educational Institution of Higher Education «Ural State Medical University» of the Ministry of Health of the Russian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Уральский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииState Budget Institution «Kurgan Regional Oncological Center»Государственное бюджетное учреждение «Курганский областной онкологический диспансер»16042020121324316042021Copyright ©; 2020, Ivliev D.S., Lyulin S.V., Balaev P.I.Copyright ©; 2020, Ивлиев Д.С., Люлин С.В., Балаев П.И.2020Ivliev D.S., Lyulin S.V., Balaev P.I.Ивлиев Д.С., Люлин С.В., Балаев П.И.https://creativecommons.org/licenses/by/4.0https://sarbon.abvpress.ru/jour/article/view/79

Metastasis of malignant tumors to the spine is a common problem in cancer patients and occurs through the hematogenous route. The main symptoms of spinal metastases are pain and neurological disorders. Modern imaging methods make it possible to verify tumor metastases. Indications for surgical treatments are determined with the help of prognostic scales, which also can help predict the treatment results. The optimal treatment is the combination of surgical treatment and radiation therapy. The sequence of surgical treatment and radiation therapy is still debatable. Systemic therapy is also an integral part of long-term control of spinal metastases and depends on the histological structure of the tumor and its ability to respond to drug exposure. Today there is no consensus and an unambiguous standardized, scientifically substantiated approach to solve the existing problem. However, further study of it will be able to provide the choice of the optimal algorithm for curation of patients with metastatic spinal lesions.

Метастазирование злокачественных опухолей в позвоночник является распространенной проблемой онкологических пациентов и происходит гематогенным путем. Проявляются метастазы позвоночника болью и неврологическими расстройствами. Современные методы визуализации позволяют верифицировать опухолевые поражения. С помощью прогностических шкал определяются показания к хирургическому лечению и прогнозируются его результаты. Оптимальным является сочетание хирургического лечения и лучевой терапии. Очередность проведения хирургического лечения и лучевой терапии по-прежнему остается дискутабельной. Системная терапия также является неотъемлемой частью долгосрочного контроля над спинальными метастазами и зависит от гистологической структуры опухоли и ее способности реагировать на медикаментозное воздействие. На сегодняшний день нет единства взглядов и однозначного стандартизированного, научно обоснованного подхода к решению существующей проблемы, однако дальнейшее ее изучение сможет обеспечить выбор оптимального алгоритма курации пациентов с метастатическим поражением позвоночника.

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